GVAX : Cell Genesys : Vaccine

Granulocyte-Macrophage Colony-Stimulating Factor Gene-Modified Autologous Tumor Vaccines in NSCLC (JNCI Cancer Spectrum)
Reports encouraging results of a phase I/II multicenter trial in patients with NSCLC of the feasibility, safety and efficacy of vaccination with autologous tumor cells genetically modified with an adenoviral vector (Ad-GM) to secrete human granulocyte-macrophage colony-stimulating factor (GM-CSF). [2/04]

Vaccination with Irradiated Autologous Tumor Cells Engineered to Secrete GM-CSF Augments Antitumor Activity in Some Patients with Metastatic NSCLC (Journal of Clinical Oncology)
Reports results of a phase I study that found vaccination with irradiated autologous NSCLC cells engineered to secrete granulocyte-macrophage colony-stimulating factor (GM-CSF) enhances antitumor immunity in some patients with metastatic NSCLC. [2/03]